Version 2 2023-06-30, 11:30Version 2 2023-06-30, 11:30
Version 1 2023-06-05, 20:35Version 1 2023-06-05, 20:35
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posted on 2023-06-30, 11:30authored byLayla A. Abushamat, Lauren Sayres, Rebecca Jeffers, Chloe Nielsen, Linda A. Barbour, Adnin Zaman
Suboptimal glycemic control among women with type 1 or type 2 diabetes before conception and during the early part of pregnancy is a powerful risk factor for fetal anomalies, macrosomia, and stillbirth. Major congenital anomalies occur in up to 25–30% of infants of women with type 1 or type 2 diabetes (1). Hyperglycemia during fetal organogenesis (5–8 weeks after the last menstrual period) is a considerable teratogen, and, consequentially, the risk of fetal anomalies related to preexisting maternal diabetes can be reduced to background risk when glycemic control is at goal.
Funding
American Diabetes Association
1-21-CMF-003
U.S. Department of Health and Human Services >
National Institutes of Health >
National Institute of Diabetes and Digestive and Kidney Diseases
F32 DK123878