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Type 1 diabetes in people hospitalized for COVID-19: new insights from the CORONADO study

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posted on 2020-08-28, 01:01 authored by Matthieu Wargny, Pierre Gourdy, Lisa Ludwig, Dominique Seret-Bégué, Olivier Bourron, Patrice Darmon, Coralie Amadou, Matthieu Pichelin, Louis Potier, Charles Thivolet, Jean-François Gautier, Samy Hadjadj, Bertrand Cariou, the CORONADO investigators
Since the start of the COVID-19 pandemic, patients with diabetes were rapidly recognized as a high-risk population for severe disease. Indeed, a high prevalence of diabetes among patients with COVID-19 who required hospitalization has been consistently reported, reaching 33.8% in 5,700 people hospitalized for COVID-19 in New York City area (1). In addition, diabetes was associated with more than a double risk of intensive care unit (ICU) admission and more than a triple risk of death (2). However, precise data regarding the type of diabetes are scarce. We report here the clinical characteristics and early prognosis of patients with type 1 diabetes (T1D) hospitalized for COVID-19 in the nationwide multicenter observational CORONADO (CORONAvirus-SARS-CoV-2 and Diabetes Outcomes) study (3).

Funding

This study received the following funding: the Fondation Francophone de Recherche sur le Diabète (FFRD), supported by Novo Nordisk, MSD, Abbott, AstraZeneca, Lilly and FFD (Fédération Française des Diabétiques) – CORONADO initiative emergency grant; Société Francophone du Diabète (SFD) – CORONADO initiative emergency grant; Air Liquide Health Care international. CORONADO emergency grant; PHRC National COVID-19 Hospitalization and Care Organization Division (DHOS) as part of the Hospital Clinical Research Program (PHRC COVID-19-20-0138). All research facilities are acknowledged for providing research associates and research technicians for clinical investigations pro bono. The funders of the study had no role in study design, data collection, data analysis, data interpretation or writing of the report. The corresponding author (BC) had full access to all the data in the study and had final responsibility for the decision to submit for publication.

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    Diabetes Care

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    Type 1Infectious DiseaseVirusPrevalencePrognosisClinical Sciences not elsewhere classified

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