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The Nonlinear Relationship Between Psoas Cross-sectional Area and BMI: A New Observation and Its Insights into Diabetes Remission After Roux-en-Y Gastric Bypass

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posted on 2021-10-13, 21:18 authored by Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han, Weiping Jia

OBJECTIVE

To explore the potential relevance of muscle mass as a variable contributor to body mass index (BMI) on BMI limitations in predicting diabetes remission (DR) after Roux-en-Y gastric bypass (RYGB).

RESEARCH DESIGN AND METHODS

We evaluated the relationship between muscle mass and BMI in 501 patients with type 2 diabetes mellitus and overweight or obesity. Of which 186 patients who underwent RYGB were studied to determine the role of baseline muscle mass and BMI in predicting DR. Muscle mass was assessed by estimated fat-free mass index (eFFMI) and psoas cross-sectional area (CSA).

RESULTS

A non-linear relationship existed between psoas CSA and BMI, whereas psoas CSA showed a highly positive correlation with eFFMI. Baseline psoas CSA and eFFMI were better than BMI for predicting 1- and 5-year DR.

CONCLUSIONS

The non-linear relationship between muscle mass and BMI may partially contribute to BMI limitations in predicting DR after RYGB.