posted on 2020-12-10, 21:55authored byJessica L. Dunne, Anne Koralova, Jessie Sutphin, Jesse S. Bushman, Barbara Fontanals-Ciera, Joshua R. Coulter, Campbell T. Hutton, Marian J Rewers, Carol Mansfield
<a><b>Objective:</b> The purpose of this
study was to use a discrete-choice experiment methodology to understand the
relative importance of the attributes of screening tests for type 1 diabetes
among parents and pediatricians in the United States.</a>
<p><b>Research Design
and Methods:</b> Online surveys presented hypothetical Screening Test profiles from
which respondents chose their preferred test profile. Survey attributes were
based on likely screening test options and included the mode of administration,
where and when the test was conducted, the type of education and monitoring
available to lower the risk of diabetic ketoacidosis (DKA), and whether a
treatment was available that would delay onset of insulin dependence. Data were
analyzed using random-parameters logit models.</p>
<p><b>Results:</b> Parents
placed the highest relative importance on monitoring programs that could reduce
the risk of DKA to 1%, followed by treatment to delay onset of insulin
dependence by 1 or 2 years, and, finally, avoiding a $50 out-of-pocket
cost. Pediatricians placed equal importance on monitoring programs that reduced
a patient’s risk of DKA to 1% and on avoiding a $50 out-of-pocket cost for the
screening test, followed by the option of a treatment to delay the onset of
insulin dependence. The mode of administration and location and timing of the screening
were much less important to both parents and
pediatricians<i>.</i></p>
<p><b>Conclusions:</b> Parents
and pediatricians preferred screening tests that were accompanied by education
and monitoring plans to reduce the risk of DKA, had available treatment to
delay type 1 diabetes, and had lower out-of-pocket costs.</p>
Funding
RTI Health Solutions received funding under a research contract with JDRF under grant # 2-PAR-2018-560-I-X to conduct this study and provide editorial support in the form of manuscript writing, styling, and submission. The Leona M. and Harry B. Helmsley Charitable Trust provided JDRF with funding for this project.