posted on 2021-03-01, 17:41authored byMary E. Lacy, Rachel A. Whitmer, Sei J. Lee, Robert J. Rushakoff, Mark J. Pletcher
This
retrospective study examined changes in medication orders as a risk factor for
future acute hypoglycemic events. The investigators identified factors
associated with acute hypoglycemic events resulting in emergency department visits
or inpatient admissions. Non-Hispanic Black race, chronic kidney disease,
insulin at baseline, and non-private insurance were associated with higher risk
of an acute hypoglycemic event, whereas age, sex, and A1C were not. After
adjustment for other risk factors, changes in insulin orders after A1C measurement
were associated with a 1.5 times higher risk of an acute hypoglycemia (adjusted
hazard ratio 1.48, 95% CI 1.08–2.03). These results further understanding of
risk factors and clinical processes relevant to predicting and preventing acute
hypoglycemia.
Funding
U.S. Department of Health and Human Services > National Institutes of Health > National Center for Advancing Translational Sciences KL2TR001996
U.S. Department of Health and Human Services > National Institutes of Health > National Institute on Aging R01 AG047500 R01AG047897 R01AG057751 T32 AG049663
Patient-Centered Outcomes Research Institute PPRN-1306-04709