Has COVID-19 delayed the diagnosis and worsened the presentation of type 1 diabetes in children?
figureposted on 10.08.2020 by Ivana Rabbone, Riccardo Schiaffini, Valentino Cherubini, Claudio Maffeis, Andrea Scaramuzza, the Italian Society for Pediatric Endocrinology and Diabetes
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
Objective: To evaluate if the diagnosis of pediatric type 1 diabetes or its acute complications changed during the early phase of the COVID-19 pandemic in Italy.
Research Design and Methods: This was a cross-sectional, web-based survey of all Italian pediatric diabetes centers to collect diabetes, diabetes ketoacidosis (DKA), and COVID-19 data in patients presenting with new-onset or established type 1 diabetes between February 20 and April 14 in 2019 and 2020.
Results: 53/68 centers (77.9%) responded. There was a 23% reduction in new diabetes cases in 2020 compared to 2019. Among those newly diagnosed patient who presented in DKA, the proportion with severe DKA was 44.3% in 2020 vs 36.1% in 2019, p = 0.03. There were no differences in acute complications. Eight patients with asymptomatic or mild COVID-19 had laboratory-confirmed SARS-CoV-2.
Conclusions: The COVID-19 pandemic might have altered diabetes presentation and DKA severity. Preparing for any “second wave” requires strategies to educate and reassure parents about timely ED attendance for non-COVID-19 symptoms.