Analysis of attained height and diabetes among 554,122 adults across 25 low- and middle-income countries
Research Design and Methods: We pooled individual-level data from nationally representative surveys in LMICs that included anthropometric measurements and diabetes biomarkers. We calculated odds ratios (ORs) for the relationship between attained adult height and diabetes using multilevel mixed-effects logistic regression models. We estimated ORs for the pooled sample, major world regions, and individual countries, in addition to stratifying all analyses by sex. We examined heterogeneity by individual-level characteristics.
Results: Our sample included 554,122 individuals across 25 population-based surveys. Average height was 161.7 cm (95% CI: 161.2–162.3) and the crude prevalence of diabetes was 7.5% (95% CI: 6.9–8.2). We found no relationship between adult height and diabetes across LMICs globally or in most world regions. When stratifying our sample by country and sex, we found an inverse association between adult height and diabetes in 5% of analyses (2/50). Results were robust to alternative model specifications.
Conclusions: Adult height is not associated with diabetes across LMICs. Environmental factors in early life reflected in attained adult height likely differ from those predisposing individuals for diabetes.